artículo académico

• In vivo neutralization of dendrotoxin-mediated neurotoxicity of black mamba venom by oligoclonal human IgG antibodies.  Nature Communications.  9:3928. 2018
• Cytotoxic Clerodane Diterpenes from Zuelania guidonia.  Journal of Natural Products.  77:455-463. 2014
• Estudio de cuatro plantas con uso medicinal tradicional cultivadas en las regiones Huetar Norte y Atlántica de Costa Rica/ Study of four plants with traditional medicinal use from Costa Rica’s Huetar Norte and Huetar Atlantica regions.  Tecnología en Marcha.  27:69-77. 2014
• New Clerodane diterpenes from Zuelania guidonia.  Docencia universitaria en pregrado en ciencias de la salud.  78. 2012
• Snake venomics and antivenomics of Protobothrops mucrosquamatus and Viridovipera stejnegeri from Taiwan: Keys to understand the variable immune response in horses.  Journal of Proteomics.  75:5628-5645. 2012
• Atherosclerosis.  Journal of Proteome Research.  10:1266-1280. 2011
• Chemical constituents from Zanthoxylum setulosum (Rutaceae) | Costituyentes químicos de Zanthoxylum setulosum (Rutaceae).  Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromáticas.  10:155-158. 2011
• Two new 3,4-seco-ent-kaurenes and other constituents from the Costa Rican endemic species Croton megistocarpus.  Helvetica Chimica Acta.  94:1888-1892. 2011
• Pre-treatment serum fatty acid levels and in vitro fertilization (IVF) treatment outcome.  Fertility and Sterility.  94:S91-S92. 2010
• Lignanos de Zanthoxylum acuminatum.  Ciencia y Tecnología.  24:227-232. 2009
• Four new compounds from the non-polar extract of the plant Amyris brenesii (Rutaceae) from Costa Rica | Cuatro compuestos nuevos del extracto no polar de la planta amyris brenesii (rutaceae) de Costa Rica.  Revista de Biología Tropical.  56:1043-1051. 2008
• Clibadiolide, a sesquiterpene lactone esterified with a homoditerpene from Clibadium pittierii.  Phytochemistry.  27:1868-1870. 2007
• Ent-kaurane glycosides and sesquiterpene lactones of the hirsutinolide type from Vernonia triflosculosa.  Phytochemistry.  67:62-69. 2006
• Heliangolide, Trachyloban‐ und Villanovan‐Derivate aus Viguiera‐Arten.  European Journal of Organic Chemistry.  1984:495-502. 2006
• Nuevas lactosas sesquiterpénicas de Perymenium grande.  Ciencia y Tecnología.  24:217-226. 2006
• Sesquiterpene lactones as inhibitors of IL-8 expression in HeLa cells.  Bioorganic & Medicinal Chemistry.  14:2487-2497. 2006
• (+)-α-copaen-8-one and other constituents from Neomirandea species.  Phytochemistry.  28:938-940. 2005
• 3-Desoxyanthocyanidins from Arrabidaea chica.  Phytochemistry.  56:831-835. 2005
• Inhibitory effects of Piper umbellatum and Piper peltatum extracts towards myotoxic phospholipases A2 from Bothrops snake venoms: Isolation of 4-nerolidylcatechol as active principle.  Phytochemistry.  66:1017-1025. 2005
• Sesquiterpene lactones and other constituents from Calea prunifolia and C. Peckii.  Phytochemistry.  135:2415-2418. 2005
• Sesquiterpene lactones inhibit Yersinia invasin protein-induced IL-8 and MCP-1 production in epithelial cells.  International Journal of Medical Microbiology.  295:531-538. 2005
• Diterpenos y otros constituyentes de Croton hirtus (Euphorbiaceae)./Diterpenes and other components of Croton hirtus (Euphorbiaceae).  Revista de Biología Tropical.  52:269-285. 2004
• Quantitative Structure−Activity Relationship of Sesquiterpene Lactones as Inhibitors of the Transcription Factor NF-κB.  Journal of Medicinal Chemistry.  47:6042-6054. 2004
• Sesquiterpene Lactones from Montanoa hibiscifolia That Inhibit the Transcription Factor NF-κB.  Journal of Natural Products.  67:622-630. 2004
• Sesquiterpene lactones inhibit luciferase but not β-galactosidase activity in vitro and ex vivo.  Analytical Biochemistry.  328:147-154. 2004
• Effect of sesquiterpene lactones on the expression of the activation marker CD69 and of IL-2 in T-lymphocytes in whole blood.  Biochemical Pharmacology.  65:1551-1563. 2003
• Studies of ent-kaurane diterpenes from Oyedaea verbesinoides for their inhibitory activity on vascular smooth muscle contraction.  Phytochemistry.  63:391-396. 2003
• The effect of sesquiterpene lactones on the human neutrophil elastase.  Biochemical Pharmacology.  65:897-903. 2003
• Sesquiterpene Lactones as inhibitors of human neutrophil elastase.  Bioorganic & Medicinal Chemistry.  10:2855-2861. 2002
• Cysteine 38 in p65/NF-kB Plays a Crucial Role in DNA Binding Inhibition by Sesquiterpene Lactones.  Journal of Biological Chemistry.  276:13-20. 2001
• Diterpenes and other constituents from Croton draco (Euphorbiaceae).  Revista de Biología Tropical.  49:259-264. 2001
• Inhibition of inflammatory cytokine production and lymphocyte proliferation by structurally different sesquiterpene lactones correlates with their effect on activation of NF-κB.  Biochemical Pharmacology.  62:795-801. 2001
• Inhibition of the Transcription Factor NF-κB by Sesquiterpene Lactones from Podachaenium eminens 1.  Docencia universitaria en pregrado en ciencias de la salud.  66:591-595. 2000
• Study of sesquiterpene lactones from Milleria quinqueflora on their anti-inflammatory activity using the transcription factor NF-κB as molecular target.  Phytochemistry.  53:257-263. 2000
• Inhibition of transcription factor NF-kappa B by sesquiterpene lactones: a proposed molecular mechanism of action.  Bioorganic & Medicinal Chemistry.  7:2343-2352. 1999
• Study of Three Sesquiterpene Lactones from Tithonia diversifolia on their Anti-Inflammatory Activity Using the Transcription Factor NF-κB and Enzymes of the Arachidonic Acid Pathway as Targets.  Docencia universitaria en pregrado en ciencias de la salud.  64:588-593. 1998
• Cardenolide glycosides: From Thevetia ahouai (LINN.) A.DC..  Chemical & Pharmaceutical Bulletin.  45:1536-1538. 1997
• Structures and Antiproliferative Activity of Saponins from Sechium pittieri and S. talamancense..  Chemical & Pharmaceutical Bulletin.  45:349-358. 1997
• Constituents of two Acalypha species.  Phytochemistry.  41:851-853. 1996
• Rigidol, an unusual diterpene from Sapium rigidifolium.  Phytochemistry.  33:1465-1468. 1993
• Melampolides from Oyedaea verbesinoides.  Phytochemistry.  31:2894-2896. 1992
• Sesquiterpene lactones from Koanophyllon albicaule.  Phytochemistry.  31:3143-3146. 1992
• Sesquiterpene lactones from two Tithonia species.  Phytochemistry.  31:3139-3141. 1992
• Kaurene derivatives from Lasianthea fruticosa, revision of stereochemistry of related compounds.  Phytochemistry.  30:1712-1714. 1991
• Glaucolides from Spiracantha cornifolia.  Phytochemistry.  29:3030-3031. 1990
• Ent-clerodane derivatives and other constituents from representatives of the subgenus Ageratina.  Phytochemistry.  28:139-141. 1989
• Germacranolides from Mikania species.  Phytochemistry.  28:527-530. 1989
• Heliangolides from Viguiera sylvatica.  Phytochemistry.  28:2737-2740. 1989
• Germacranolides and other constituents from Ageratina species.  Phytochemistry.  27:2893-2897. 1988
• Seco-manool and other constituents from Fleischmannia microstemon.  Phytochemistry.  27:3322-3323. 1988
• Further seco-labdanes from Hebeclinium macrophyllum.  Phytochemistry.  26:2331-2335. 1987
• Further sesquiterpene lactones from costa rican eupatorieae.  Phytochemistry.  26:451-455. 1987
• Millerenolides, sesquiterpene lactones from Milleria quinqueflora.  Phytochemistry.  26:2011-2017. 1987
• Further Sesquiterpene Lactones from Elephantopus mollis and Centratherum punctatum.  Docencia universitaria en pregrado en ciencias de la salud.  52:29-32. 1986
• Further pyrrolizidine alkaloids and furoeremophilanes from Senecio species.  Phytochemistry.  25:1151-1159. 1986
• Poskeanolide, a seco-germacranolide and other sesquiterpene lactones from Vernonia species.  Phytochemistry.  25:1359-1364. 1986
• Sesquiterpene lactones from Mikania species.  Phytochemistry.  25:1750-1752. 1986
• 4β,19-Epoxy-norkaurene and other diterpenes from Mikania banisteriae.  Phytochemistry.  24:2450-2451. 1985
• 5-Methylcumarin-Derivate ausLycoseris latifolia.  European Journal of Organic Chemistry.  1985:1367-1376. 1985
• ChemInform Abstract: 5-METHYLCOUMARIN DERIVATIVES FROM LYCOSERIS LATIFOLIA.  Natural Product Research.  16. 1985
• Cuauthemone derivatives from Tessaria integrifolia and Pluchea symphytifolia.  Phytochemistry.  24:3053-3055. 1985
• Two further 6,12-cis-germacranolides from Montanoa tomentosa subsp. xanthiifolia.  Phytochemistry.  24:2449-2450. 1985
• A New Type of Sesquiterpene and Acorane Derivative from Calea prunifolia.  Journal of Natural Products.  47:802-808. 1984
• ChemInform Abstract: HELIANGOLIDES AND TRACHYLOBANE AND VILLANOVANE DERIVATIVES FROM VIGUIERA SPECIE.  Natural Product Research.  15. 1984
• Further 6,12-cis-Germacranolides and Eudesmanolides from Montanoa Species.  Journal of Natural Products.  47:663-672. 1984
• ChemInform Abstract: DECATHIELEANOLIDE, A DIMERIC GUAIANOLIDE FROM DECACHAETA THIELEANA.  Natural Product Research.  14. 1983
• Decathieleanolid, ein dimeres Guajanolid ausDecachaeta thieleana.  European Journal of Organic Chemistry.  1983:974-981. 1983
• Estudio preliminar sobre factores inhibidores de enzimas proteolíticas en la harina de pejibaye (Bactris gasipaes).  Revista de Biología Tropical.  31:227-231. 1983
• Germacra-1(10),4-dien-cis-6,12-olides and elemanolides from Montanoa atriplicifolia.  Phytochemistry.  22:1223-1225. 1983