artículo académico

• Bornyl cinnamate derivatives with anti-inflammatory activity from Verbesina turbacensis.  Pharmaceutical and Pharmacological Letters.  10:115-118. 2018
• Actinoramide A Identified as a Potent Antimalarial from Titration-Based Screening of Marine Natural Product Extracts.  Journal of Natural Products.  78:2411-2422. 2015
• Cardiovascular disease, chronic kidney disease, and diabetes mortality burden of cardiometabolic risk factors from 1980 to 2010: a comparative risk assessment.  Lancet Diabetes Diabetes & Endocrinology.  2:634-647. 2014
• Cytotoxic Clerodane Diterpenes from Zuelania guidonia.  Journal of Natural Products.  77:455-463. 2014
• Estudio preliminar del potencial bioactivo de la Annona cherimola (anona) y Prunus domestica (ciruelo) cultivadas en Costa Rica.  Tecnología en Marcha.  27:37-44. 2014
• Tropical dry forests in Latin America: analyzing history of land use and present socio-ecological struggles. 2013
• Backbone flexibility controls the activity and specificity of a protein-protein interface – specificity in snake venom metalloproteases (SVMPs).  Journal of the American Chemical Society.  132:10330-10337. 2010
• Ent-kaurane glycosides and sesquiterpene lactones of the hirsutinolide type from Vernonia triflosculosa.  Phytochemistry.  67:62-69. 2006
• Sesquiterpene lactones as inhibitors of IL-8 expression in HeLa cells.  Bioorganic & Medicinal Chemistry.  14:2487-2497. 2006
• 3-Desoxyanthocyanidins from Arrabidaea chica.  Phytochemistry.  56:831-835. 2005
• Sesquiterpene lactones inhibit Yersinia invasin protein-induced IL-8 and MCP-1 production in epithelial cells.  International Journal of Medical Microbiology.  295:531-538. 2005
• Quantitative Structure−Activity Relationship of Sesquiterpene Lactones as Inhibitors of the Transcription Factor NF-κB.  Journal of Medicinal Chemistry.  47:6042-6054. 2004
• Role of cysteine residues of p65/NF-κB on the inhibition by the sesquiterpene lactone parthenolide and N-ethyl maleimide, and on its transactivating potential.  Life Sciences.  75:841-856. 2004
• Sesquiterpene Lactones from Montanoa hibiscifolia That Inhibit the Transcription Factor NF-κB.  Journal of Natural Products.  67:622-630. 2004
• Sesquiterpene lactones inhibit luciferase but not β-galactosidase activity in vitro and ex vivo.  Analytical Biochemistry.  328:147-154. 2004
• Effect of sesquiterpene lactones on the expression of the activation marker CD69 and of IL-2 in T-lymphocytes in whole blood.  Biochemical Pharmacology.  65:1551-1563. 2003
• Studies of ent-kaurane diterpenes from Oyedaea verbesinoides for their inhibitory activity on vascular smooth muscle contraction.  Phytochemistry.  63:391-396. 2003
• The effect of sesquiterpene lactones on the human neutrophil elastase.  Biochemical Pharmacology.  65:897-903. 2003
• Guaianolides from Viguiera gardneri inhibit the transcription factor NF-κB.  Phytochemistry.  60:733-740. 2002
• Sesquiterpene Lactones as inhibitors of human neutrophil elastase.  Bioorganic & Medicinal Chemistry.  10:2855-2861. 2002
• Cysteine 38 in p65/NF-kB Plays a Crucial Role in DNA Binding Inhibition by Sesquiterpene Lactones.  Journal of Biological Chemistry.  276:13-20. 2001
• Germacranolides from Mikania guaco.  Phytochemistry.  56:475-489. 2001
• Inhibition of inflammatory cytokine production and lymphocyte proliferation by structurally different sesquiterpene lactones correlates with their effect on activation of NF-κB.  Biochemical Pharmacology.  62:795-801. 2001
• Inhibition of the Transcription Factor NF-κB by Sesquiterpene Lactones from Podachaenium eminens 1.  Docencia universitaria en pregrado en ciencias de la salud.  66:591-595. 2000
• Study of sesquiterpene lactones from Milleria quinqueflora on their anti-inflammatory activity using the transcription factor NF-κB as molecular target.  Phytochemistry.  53:257-263. 2000
• Inhibition of granulocyte elastase activity by caffeic acid derivatives.  Pharmazie.  54:712. 1999
• Inhibition of transcription factor NF-kappa B by sesquiterpene lactones: a proposed molecular mechanism of action.  Bioorganic & Medicinal Chemistry.  7:2343-2352. 1999
• Study of Three Sesquiterpene Lactones from Tithonia diversifolia on their Anti-Inflammatory Activity Using the Transcription Factor NF-κB and Enzymes of the Arachidonic Acid Pathway as Targets.  Docencia universitaria en pregrado en ciencias de la salud.  64:588-593. 1998
• Diterpenes and sesquiterpenes from Mikania banisteriae.  Phytochemistry.  46:161-164. 1997