Estudio ultraestructural de las alteractiones locales inducidas en raton blanco por el veneno de Bothrops picadoi de Costa Rica Artículo académico uri icon


  • The pathogenesis of local lesions induced by Bothrops picadoi venom was studied at the electron microscopic level. White mice were injected i.m. with 100 μg of venom. A strong hemorrhagic action was the earliest and most prominent local effect observed in this study. In skeletal muscle fibers, rupture of the sarcolemma was observed and myofibril structure was drastically affected, showing amorphous masses of myofilaments. Myelin layers in many axons were disorganized.

fecha de publicación

  • 1984