publicaciones seleccionadas
-
artículo académico
- Cranberry proanthocyanidin-chitosan hybrid nanoparticles as a potential inhibitor of extra-intestinal pathogenic Escherichia coli invasion of gut epithelial cells. International Journal of Biological Macromolecules. 111:415-420. 2018
- Brucella neotomae infection in humans, Costa Rica. Emerging Infectious Diseases. 23:997-1000. 2017
- Dietary fat and semen quality among men attending a fertility clinic. Human Reproduction. 27:1466-1474. 2016
- Extensión: TEC y Sociedad en mutuo desarrollo. Investiga. TEC. 1:3-4. 2016
- Standardization of assays for testing the neutralizing ability of antivenoms. Toxicon. 28:1127-1129. 2012
- Neutralization of crotaline snake venoms from Central and South America by antivenoms produced in Brazil and Costa Rica. Toxicon. 38:1429-1441. 2011
- Novel Semiautomated Method for Assessing in Vitro Cellular Antioxidant Activity Using the Light-Scattering Properties of Human Erythrocytes. Journal of Agricultural and Food Chemistry. 58:1455-1461. 2010
- Comparative study on the ability of IgG and Fab sheep antivenoms to neutralize local hemorrhage, edema and myonecrosis induced by Bothrops asper (terciopelo) snake venom. Cuadernos de Investigación UNED (UNED Research Journal). 1:233-244. 2009
- Efficacy and safety of two whole IgG polyvalent antivenoms, refined by caprylic acid fractionation with or without β-propiolactone, in the treatment of Bothrops asper bites in Colombia. Transactions of the Royal Society of Tropical Medicine and Hygiene. 100:1173-1182. 2006
- Neutralization of four Peruvian Bothrops sp. snake venoms by polyvalent antivenoms produced in Perú and Costa Rica: Preclinical assessment. Acta Tropica. 93:85-95. 2005
- Pan-African polyspecific antivenom produced by caprylic acid purification of horse IgG: An alternative to the antivenom crisis in Africa. Transactions of the Royal Society of Tropical Medicine and Hygiene. 99:468-475. 2005
- Effect of preservatives on IgG aggregation, complement-activating effect and hypotensive activity of horse polyvalent antivenom used in snakebite envenomation. Biologicals. 30:143-151. 2002
- Genome Biology and Evolution. Revista de Biología Tropical. 50:337-346. 2002
- A randomized blinded clinical trial of two antivenoms, prepared by caprylic acid or ammonium sulphate fractionation of IgG, in Bothrops and Porthidium snake bites in Colombia: Correlation between safety and biochemical characteristics of antivenoms. Toxicon. 37:895-908. 1999
- Comparative study on the ability of IgG and F(ab')2 antivenoms to neutralize lethal and myotoxic effects induced by Micrurus nigrocinctus (coral snake) venom. American Journal of Tropical Medicine and Hygiene. 61:266-271. 1999
- Envenamiento por mordedura de serpiente en Costa Rica en 1996: Epidemiología y consideraciones clínicas. Acta Médica Costarricense. 41:23-29. 1999
- Instituto Clodomiro Picado: Ciencia y tecnología endógenas en la solución de un problema de salud pública en centroamérica. Interciencia. 24:182-186. 1999
- Neutralization, by a monospecific Bothrops lanceolatus antivenom, of toxic activities induced by homologous and heterologous Bothirops snake venoms. Toxicon. 37:551-557. 1999
-
Inhibition by CaNa
2 EDTA of local tissue damage induced by Bothrops asper (terciopelo) venom: Application in horse immunization for antivenom production. Toxicon. 36:321-331. 1998 - Neutralization of local tissue damage induced by Bothrops asper (terciopelo) snake venom. Toxicon. 36:1529-1538. 1998
- Immunoglobulin G and F(ab')2 polyvalent antivenoms do not differ in their ability to neutralize hemorrhage, edema and myonecrosis induced by bothrops asper (terciopelo) snake venom. Toxicon. 35:1627-1637. 1997
- Snakebite mortality in Costa Rica. Toxicon. 35:1639-1643. 1997
- Evaluacion de la capacidad de cuatro antivenenos comerciales para neutralizar el veneno de la serpiente Bothrops asper (terciopelo) de Costa Rica. Toxicon. 33:1242-1247. 1995
- Caprylic acid fractionation of hyperimmune horse plasma: Description of a simple procedure for antivenom production. Toxicon. 32:351-363. 1994
- Turbidity of hyperimmune equine antivenom: The role of phenol and serum lipoproteins. Toxicon. 31:61-66. 1993
- Experimental myonecrosis induced by the venoms of South American Micrurus (coral snakes). Toxicon. 30:1299-1302. 1992
- Biochemical and pharmacological similarities between the venoms of newborn Crotalus durissus durissus and adult Crotalus durissus terrificus rattlesnakes. Toxicon. 29:1273-1277. 1991
- Enlace al artículo. Brazilian Journal of Medical and Biological Research. 24:701-710. 1991
- Quantitation by enzyme-immunoassay of antibodies against bothrops myotoxins in four commercially-available antivenoms. Toxicon. 29:695-702. 1991
- Effect of storage temperature on the stability of the liquid polyvalent antivenom produced in Costa Rica. Toxicon. 28:101-105. 1990
- International Journal of Renewable Energy & Biofuels. Toxicon. 28:75-81. 1990
- Comparative study on coagulant, defibrinating, fibrinolytic and fibrinogenolytic activities of Costa Rican crotaline snake venoms and their neutralization by a polyvalent antivenom. Toxicon. 27:841-848. 1989
- El suero antiofídico polivalente producido en Costa Rica: Estabilidad y capacidad neutralizante. Revista Costarricense de Ciencias Medicas. 9:155-169. 1988
- Ability of a polyvalent antivenom to neutralize the venom of Lachesis Muta Melanocephala, a new Costa Rican subspecies of the bushmaster. Toxicon. 25:713-720. 1987
- Effects of a myotoxic phospholipase A2 isolated from Bothrops asper venom on skeletal muscle sarcoplasmic reticulum. Toxicon. 25:1244-1248. 1987
- Neutralization of toxic and enzyme activities of 4 venoms from snakes of Guatemala and Honduras by the polyvalent antivenin produced in Costa Rica | Neutralización de las actividades tóxicas y enzimáticas de cuatro venenos de serpientes de Guatemala y Honduras por el antiveneno polivalente producido en Costa Rica.. Revista de Biología Tropical. 35:59-67. 1987
- Neutralization of proteolytic and hemorrhagic activities of Costa Rican snake venoms by a polyvalent antivenom. Toxicon. 23:887-893. 1985