Abstracto
- The antimicrobial resistance boosted the development of alternative wound healing therapies. A successful example is Medihoney®. To our knowledge, this is the first report of minimum inhibitory concentration (MIC) assays of Meliponini honeys against antibiotic-resistant isolates of Staphylococcus aureus and Pseudomonas aeruginosa coming from infected hospital patients in comparison to Medihoney®. The samples under study belonged to the Tetragonisca angustula (n = 36) and Melipona beecheii (n = 21) species. 64 % of the T. angustula and 10 % of the M. beecheii honeys inhibited all the antibiotic-resistant bacteria. Medihoney® was active against every strain tested with exception of a P. aeruginosa isolate. Costa Rican T. angustula honeys can be selected according to their broad-spectrum antimicrobial activity. Moreover, such selection can render MICs similar to Medihoney® in order to carry on further research and development towards a novel antimicrobial topical therapy for burn and wound healing.