artículo académico

• Brucella sequence Type 27 isolated from Dwarf Sperm Whale (Kogia sima) stranded in the Costa Rican Pacific Coast.  Access Microbiology.  1. 2019
• Neutrophils Dampen Adaptive Immunity in Brucellosis.  Infection and Immunity.  87:1-14. 2019
• Neutrophils as Trojan horse vehicles for Brucella abortus macrophage infection.  Frontiers in Immunology.  10:1012. 2019
• Brucella abortus Senses the Intracellular Environment through the BvrR/BvrS Two-Component System, Which Allows B. abortus To Adapt to Its Replicative Niche.  Infection and Immunity.  86:1-15. 2018
• Depletion of Complement Enhances the Clearance of Brucella abortus in Mice.  Infection and Immunity.  86:1-8. 2018
• Two Groups of Cocirculating, Epidemic Clostridiodes difficile Strains Microdiversify through Different Mechanisms.  Genome Biology and Evolution.  10:982-998. 2018
• A Clostridium difficile Lineage Endemic to Costa Rican Hospitals Is Multidrug Resistant by Acquisition of Chromosomal Mutations and Novel Mobile Genetic Elements .  Antimicrobial Agents and Chemotherapy.  61:e02054-16. 2017
• Brucella Genetic Variability in Wildlife Marine Mammals Populations Relates to Host Preference and Ocean Distribution.  Genome Biology and Evolution.  9:1901-1912. 2017
• Brucella neotomae infection in humans, Costa Rica.  Emerging Infectious Diseases.  23:997-1000. 2017
• Brucellosis caused by the wood rat pathogen Brucella neotomae: two case reports.  Journal of Medical Case Reports.  11:352. 2017
• Brucellosis in mammals of Costa Rica: an epidemiological survey.  PLoS ONE.  12:a0182644. 2017
• Epidemiology of bovine brucellosis in Costa Rica: Lessons learned from failures in the control of the disease.  PLoS ONE.  12:e0182380. 2017
• Neighbourhood structure and light availability influence the variations in plant design of shrubs in two cloud forests of different successional status.  Annals of Botany.  118:23-34. 2017
• A MLST Clade 2 Clostridium difficile strain with a variant TcdB induces severe inflammatory and oxidative response associated with mucosal disruption. .  Anaerobe.  40:76-84. 2016
• Analysis of TcdB Proteins within the Hypervirulent Clade 2 Reveals an Impact of RhoA Glucosylation on Clostridium difficile Proinflammatory Activities. .  Infection and Immunity.  84:856-865. 2016
• Brucella abortus strain 2308 Wisconsin genome: importance of the definition of reference strains.  Frontiers in Microbiology.  7:1557. 2016
• N-formyl-perosamine surface homopolysaccharides hinder the recognition of Brucella abortus by mouse neutrophils.  Infection and Immunity.  84:1712-1721. 2016
• Brucella abortus induces the premature death of human neutrophils through the action of its lipopolysaccharide.  PLos Pathogens.  11:e1004853. 2015
• Brucella canis is an intracellular pathogen that induces a lower proinflammatory response than smooth zoonotic counterparts.  Infection and Immunity.  83:4861-4870. 2015
• Emergence of an outbreak-associated Clostridium difficile variant with increased virulence. .  International Journal of Experimental Pathology.  53:1216-1226. 2015
• Multiscale postseismic behavior on a megathrust: The 2012 Nicoya earthquake, Costa Rica.  Geochemistry, Geophysics, Geosystems.  16:1848-1864. 2015
• Brucella ceti infection in dolphins from the Western Mediterranean sea.  BMC Veterinary Research.  10:206. 2014
• Bacterial Counts in Spleen.  Bio protocol.  3. 2013
• Brucella ceti and Brucellosis in Cetaceans.  Frontiers in Cellular and Infection Microbiology.  2:1-22. 2012
• Phenolic compounds as antiangiogenic CMG2 inhibitors from costa rican endophytic fungi.  Bioorganic & Medicinal Chemistry Letters.  22:5885-5888. 2012
• The Lipopolysaccharide Core of Brucella abortus Acts as a Shield Against Innate Immunity Recognition.  PLos Pathogens.  8:e1002675. 2012
• Brucella abortus Ornithine Lipids Are Dispensable Outer Membrane Components Devoid of a Marked Pathogen-Associated Molecular Pattern.  PLoS ONE.  6:e16030. 2011
• The struggle of neglected scientific groups: Ten years of netropica efforts to promote research in tropical diseases in central america.  PLoS Neglected Tropical Diseases.  5. 2011
• Pathology of Striped Dolphins (Stenella coeruleoalba) Infected with Brucella ceti.  Journal of Comparative Pathology.  142:347-352. 2010
• The two-component system BvrR/BvrS regulates the expression of the type IV secretion system VirB in Brucella abortus.  Journal of Bacteriology.  192:5603-5608. 2010
• Intracellular Adaptation of Brucella abortus.  Journal of Proteome Research.  8:1594-1609. 2009
• Serological Diagnosis of Brucella Infections in Odontocetes.  Clinical and Vaccine Immunology.  16:906-915. 2009
• The Differential Interaction of Brucella and Ochrobactrum with Innate Immunity Reveals Traits Related to the Evolution of Stealthy Pathogens.  PLoS ONE.  4:e5893. 2009
• Estudio de la capacidad ofiofaga y la resistencia de la zopilota (Clelia clelia, Colubridae) de Costa Rica a los venenos de serpiente.  Emerging Infectious Diseases.  14:1430-1433. 2008
• BvrR/BvrS-Controlled Outer Membrane Proteins Omp3a and Omp3b Are Not Essential for Brucella abortus Virulence.  Infection and Immunity.  75:4867-4874. 2007
• El centenario del nacimiento de Clodomiro Picado T. y el retorno del Mutacionismo.  Revista de Biología Tropical.  35:1-4. 2007
• In vitro antiviral activity of Chamaecrista nictitans (Fabaceae) against herpes simplex virus: Biological characterization of mechanisms of action.  Revista de Biología Tropical.  52:807-816. 2004
• R-Ras Glucosylation and Transient RhoA Activation Determine the Cytopathic Effect Produced by Toxin B Variants from Toxin A-negative Strains of Clostridium difficile.  Journal of Biological Chemistry.  278:7956-7963. 2003
• Activation of Rho and Rab GTPases dissociates Brucella abortus internalization from intracellular trafficking.  Cellular Microbiology.  4:663-676. 2002
• Genome Biology and Evolution.  Revista de Biología Tropical.  50:337-346. 2002
• GTPases of the Rho subfamily are required for Brucella abortus internalization in nonprofessional phagocytes: Direct activation of Cdc42.  Journal of Biological Chemistry.  276:44435-44443. 2001
• In Vivo Proteolytic Degradation of the Escherichia coli Acyltransferase HlyC.  Journal of Biological Chemistry.  276:16660-16666. 2001