artículo académico

• Brucella sequence Type 27 isolated from Dwarf Sperm Whale (Kogia sima) stranded in the Costa Rican Pacific Coast.  Access Microbiology.  1. 2019
• Corrigendum: Genetic and Phenotypic Characterization of the Etiological Agent of Canine Orchiepididymitis Smooth Brucella sp. BCCN84.3.  Frontiers in Veterinary Science.  6. 2019
• Genetic and Phenotypic Characterization of the Etiological Agent of Canine Orchiepididymitis Smooth Brucella sp. BCCN84.3.  Frontiers in Veterinary Science.  6:1-6. 2019
• Neutrophils Dampen Adaptive Immunity in Brucellosis.  Infection and Immunity.  87:1-14. 2019
• Neutrophils as Trojan horse vehicles for Brucella abortus macrophage infection.  Frontiers in Immunology.  10:1012. 2019
• Brucella abortus Senses the Intracellular Environment through the BvrR/BvrS Two-Component System, Which Allows B. abortus To Adapt to Its Replicative Niche.  Infection and Immunity.  86:1-15. 2018
• Depletion of Complement Enhances the Clearance of Brucella abortus in Mice.  Infection and Immunity.  86:1-8. 2018
• Persistence of Brucella abortus in the Bone Marrow of Infected Mice.  Journal of Immunology Research.  2018:1-8. 2018
• Brucella Genetic Variability in Wildlife Marine Mammals Populations Relates to Host Preference and Ocean Distribution.  Genome Biology and Evolution.  9:1901-1912. 2017
• Brucella neotomae infection in humans, Costa Rica.  Emerging Infectious Diseases.  23:997-1000. 2017
• Brucellosis caused by the wood rat pathogen Brucella neotomae: two case reports.  Journal of Medical Case Reports.  11:352. 2017
• Brucellosis in mammals of Costa Rica: an epidemiological survey.  PLoS ONE.  12:a0182644. 2017
• Epidemiology of bovine brucellosis in Costa Rica: Lessons learned from failures in the control of the disease.  PLoS ONE.  12:e0182380. 2017
• Human Brucella melitensis infections in southern Vietnam.  Clinical Microbiology and Infection.  23:788-790. 2017
• Síntesis y caracterización de redes elastoméricas de poliuretano (EPU) utilizado en la elaboración de calzado. II. Utilización de modelos matemáticos.  Revista Iberoamericana de Polímeros.  7:174-198. 2017
• Diez reglas sencillas para científicos con aspiraciones en países de bajos ingresos.  Reportes Científicos FACEN.  4:82-85. 2016
• Brucella abortus strain 2308 Wisconsin genome: importance of the definition of reference strains.  Frontiers in Microbiology.  7:1557. 2016
• N-formyl-perosamine surface homopolysaccharides hinder the recognition of Brucella abortus by mouse neutrophils.  Infection and Immunity.  84:1712-1721. 2016
• N-formyl-perosamine surface homopolysaccharides hinder the recognition of Brucella abortus by mouse neutrophils.  Infection and Immunity.  84:1712-1721. 2016
• Effect of geographical variation of Echis ocellatus, Naja nigricollis and Bitis arietans venoms on their neutralization by homologous and heterologous antivenoms.  Toxicon.  108:80-83. 2015
• Brucella abortus induces the premature death of human neutrophils through the action of its lipopolysaccharide.  PLos Pathogens.  11:e1004853. 2015
• Brucella canis is an intracellular pathogen that induces a lower proinflammatory response than smooth zoonotic counterparts.  Infection and Immunity.  83:4861-4870. 2015
• Emergence of an outbreak-associated Clostridium difficile variant with increased virulence. .  International Journal of Experimental Pathology.  53:1216-1226. 2015
• An electrophoretic study on phospholipase A2 isoenzymes in the venoms of Central American crotaline snakes.  Toxicon.  30:815-823. 2014
• Brucella ceti infection in dolphins from the Western Mediterranean sea.  BMC Veterinary Research.  10:206. 2014
• Retrospective and prospective perspectives on zoonotic brucellosis.  Frontiers in Microbiology.  5:213. 2014
• Bacterial Counts in Spleen.  Bio protocol.  3. 2013
• Estrada, Jose.  PLos Pathogens.  9:e1003167. 2013
• Brucella ceti and Brucellosis in Cetaceans.  Frontiers in Cellular and Infection Microbiology.  2:1-22. 2012
• Brucella β 1,2 Cyclic Glucan Is an Activator of Human and Mouse Dendritic Cells.  PLos Pathogens.  8:e1002983. 2012
• The Lipopolysaccharide Core of Brucella abortus Acts as a Shield Against Innate Immunity Recognition.  PLos Pathogens.  8:e1002675. 2012
• Brucella abortus Ornithine Lipids Are Dispensable Outer Membrane Components Devoid of a Marked Pathogen-Associated Molecular Pattern.  PLoS ONE.  6:e16030. 2011
• The struggle of neglected scientific groups: Ten years of netropica efforts to promote research in tropical diseases in central america.  PLoS Neglected Tropical Diseases.  5. 2011
• The use of green fluorescent protein as a marker for Brucella vaccines.  Vaccine.  29:577-582. 2011
• Desarrollo de las universidades públicas de Latinoamérica: una visión alternativa al modelo economicista de rentabilidad / Development of public universities in latin america: an alternative perspective to the economicist model of profitability.  Actualidades Investigativas en Educación.  10:1-14. 2010
• Docencia universitaria en pregrado en ciencias de la salud.  BMC Genomics.  11:300. 2010
• Synthetic peptides derived from the C-Terminal region of Lys49 phospholipase A2 homologues from viperidae snake venoms: Biomimetic activities and potential applications.  Current Pharmaceutical Design.  16:3224-3230. 2010
• The two-component system BvrR/BvrS regulates the expression of the type IV secretion system VirB in Brucella abortus.  Journal of Bacteriology.  192:5603-5608. 2010
• Intracellular Adaptation of Brucella abortus.  Journal of Proteome Research.  8:1594-1609. 2009
• Is Brucella an enteric pathogen?.  Nature Reviews Microbiology.  7:250. 2009
• Serological Diagnosis of Brucella Infections in Odontocetes.  Clinical and Vaccine Immunology.  16:906-915. 2009
• The Differential Interaction of Brucella and Ochrobactrum with Innate Immunity Reveals Traits Related to the Evolution of Stealthy Pathogens.  PLoS ONE.  4:e5893. 2009
• Computational biology in Costa Rica: The role of a small country in the global context of bioinformatics.  PLoS Computational Biology.  4. 2008
• Estudio de la capacidad ofiofaga y la resistencia de la zopilota (Clelia clelia, Colubridae) de Costa Rica a los venenos de serpiente.  Emerging Infectious Diseases.  14:1430-1433. 2008
• Ten simple rules for aspiring scientists in a low-income country.  PLoS Computational Biology.  4. 2008
• Factores involucrados en la adhesión al tratamiento de la diabetes mellitus tipo II en una muestra de pacientes diabéticos de la zona norte de Costa Rica: un estudio psicométrico.  Diversitas: Perspectivas en Psicología.  3:25-36. 2007
• Brucella abortus Uses a Stealthy Strategy to Avoid Activation of the Innate Immune System during the Onset of Infection.  PLoS ONE.  2:e631. 2007
• BvrR/BvrS-Controlled Outer Membrane Proteins Omp3a and Omp3b Are Not Essential for Brucella abortus Virulence.  Infection and Immunity.  75:4867-4874. 2007
• R-Ras Glucosylation and Transient RhoA Activation Determine the Cytopathic Effect Produced by Toxin B Variants from Toxin A-negative Strains of Clostridium difficile.  Journal of Biological Chemistry.  278:7956-7963. 2003
• Activation of Rho and Rab GTPases dissociates Brucella abortus internalization from intracellular trafficking.  Cellular Microbiology.  4:663-676. 2002
• Regulation of Brucella virulence by the two-component system BvrR/BvrS.  Veterinary Microbiology.  90:329-339. 2002
• The two-component system BvrR/BvrS essential for Brucella abortus virulence regulates the expression of outer membrane proteins with counterparts in members of the Rhizobiaceae.  Proceedings of the National Academy of Sciences.  99:12375-12380. 2002
• GTPases of the Rho subfamily are required for Brucella abortus internalization in nonprofessional phagocytes: Direct activation of Cdc42.  Journal of Biological Chemistry.  276:44435-44443. 2001
• In Vivo Proteolytic Degradation of the Escherichia coli Acyltransferase HlyC.  Journal of Biological Chemistry.  276:16660-16666. 2001
• Tyr→Trp-substituted peptide 115-129 of a Lys49 phospholipase A2 expresses enhanced membrane-damaging activities and reproduces its in vivo myotoxic effect.  Biochimica et Biophysica Acta - Biomembranes.  1461:19-26. 1999
• Bactericidal activity of Lys49 and Asp49 myotoxic phospholipases A2 from Bothrops asper snake venom: Synthetic Lys49 myotoxin II-(115-129)- peptide identifies its bactericidal region.  European Journal of Biochemistry.  253:452-461. 1998
• Effect of adjuvants on the antibody response of mice to Bothrops asper (Terciopelo) snake venom.  Brazilian Journal of Medical and Biological Research.  29:1337-1340. 1996
• A new method for the detection of phospholipase A2 variants: Identification of isozymes in the venoms of newborn and adult Bothrops asper (terciopelo) snakes.  Toxicon.  26:363-371. 1988
• Body distribution of Bothrops asper (terciopelo) snake venom myotoxin and its relationship to pathological changes.  Toxicon.  26:403-409. 1988
• Antibody neutralization of a myotoxin from the venom of Bothrops asper (terciopelo).  Toxicon.  25:443-449. 1987
• Detection of proteins antigenically related to Bothrops asper myotoxin in crotaline snake venoms.  Toxicon.  25:947-955. 1987
• Pharmacological activities of a toxic phospholipase a isolated from the venom of the snake Bothrops Asper.  Comparative Biochemistry and Physiology Part C: Comparative Pharmacology.  84:159-164. 1986