artículo académico

• First look into the venom of Roatan Island's critically endangered coral snake Micrurus ruatanus: Proteomic characterization, toxicity, immunorecognition and neutralization by an antivenom.  Journal of Proteomics.  198:177-185. 2019
• First look into the venom of Roatan Island's critically endangered coral snake Micrurus ruatanus: Proteomic characterization, toxicity, immunorecognition and neutralization by an antivenom.  Journal of Proteomics.  198:177-185. 2019
• Harnessing phage display technology for discovery of human IgGs targeting clinically relevant toxins from the venom of the Central American coral snake (Micrurus nigrocinctus).  Toxicon.  158:S45. 2019
• Isolation of two basic phospholipases A2 from Bothrops diporus snake venom: Comparative characterization and synergism between Asp49 and Lys49 variants.  Toxicon.  168:113-121. 2019
• Neutralizing properties of LY315920 toward snake venom group I and II myotoxic phospholipases A2.  Toxicon.  157:1-7. 2019
• Neutrophils as Trojan horse vehicles for Brucella abortus macrophage infection.  Frontiers in Immunology.  10:1012. 2019
• Proteomic profiling, functional characterization, and immunoneutralization of the venom of Porthidium porrasi, a pitviper endemic to Costa Rica.  Acta Tropica.  193:113-123. 2019
• Three-finger toxins from the venom of Micrurus tschudii tschudii (desert coral snake): Isolation and characterization of tschuditoxin-I.  Toxicon.  167:144-151. 2019
• A myotoxic Lys49 phospholipase A 2 -homologue is the major component of the venom of Bothrops cotiara from Misiones, Argentina.  Toxicon.  148:143-148. 2018
• A novel pentameric phospholipase A 2 myotoxin (PophPLA 2 ) from the venom of the pit viper Porthidium ophryomegas.  International Journal of Biological Macromolecules.  118:1-8. 2018
• Cell surface nucleolin interacts with and internalizes Bothrops asper Lys49 phospholipase A2 and mediates its toxic activity.  Scientific Reports.  8. 2018
• Characterization of a novel snake venom component: Kazal-type inhibitor-like protein from the arboreal pitviper Bothriechis schlegelii.  Biochimie.  10:61-66. 2018
• Intravascular hemolysis induced by phospholipases A2 from the venom of the Eastern coral snake, Micrurus fulvius: Functional profiles of hemolytic and non-hemolytic isoforms.  Toxicology Letters.  286:39-47. 2018
• Proteomic studies on Micrurus (coral snakes) venom reveal a dichotomy of phenotypes.  Toxicon.  150:319-320. 2018
• Unresolved issues in the understanding of the pathogenesis of local tissue damage induced by snake venoms.  Toxicon.  148:123-131. 2018
• Differential procoagulant effects of saw-scaled viper (Serpentes: Viperidae: Echis) snake venoms on human plasma and the narrow taxonomic ranges of antivenom efficacies.  Toxicology Letters.  280:159-170. 2017
• Nucleolin internalizes Bothrops asper Lys49 phospholipase A2 forming cell surface amyloid-like assemblies.  BioRxiv.  2017
• Combined venomics, venom gland transcriptomics, bioactivities, and antivenomics of two Bothrops jararaca populations from geographic isolated regions within the Brazilian Atlantic rainforest.  Journal of Proteomics.  135:73-89. 2016
• Integrative characterization of the venom of the coral snake Micrurus dumerilii (Elapidae) from Colombia: Proteome, toxicity, and cross-neutralization by antivenom.  Journal of Proteomics.  136:262-273. 2016
• Towards autotrophic tissue engineering: photosynthetic gene therapy for regeneration.  Biomaterials.  75:25-36. 2016
• Venoms of Micrurus coral snakes: Evolutionary trends in compositional patterns emerging from proteomic analyses.  Toxicon.  122:7-25. 2016
• Snake venomics of monocled cobra (Naja kaouthia) and investigation of human IgG response against venom toxins.  Toxicon.  99:23-35. 2015
• First crotoxin-like phospholipase A2 complex from a New World non-rattlesnake species: Nigroviriditoxin, from the arboreal Neotropical snake Bothriechis nigroviridis.  Toxicon.  93:144-154. 2015
• Snake venomics of Micrurus alleni and Micrurus mosquitensis from the Caribbean region of Costa Rica reveals two divergent compositional patterns in New World elapids.  Toxicon.  107:217-233. 2015
• Unveiling the nature of black mamba (Dendroaspis polylepis) venom through venomics and antivenom immunoprofiling: Identification of key toxin targets for antivenom development.  Journal of Proteomics.  119:126-142. 2015
• Production in E. coli, folding, purification and characterization of notexin with wild type sequence and with N-terminal and catalityc site mutations..  Toxicon.  88:11-20. 2014
• Synergism between basic Asp49 and Lys49 phospholipase A2 myotoxins of viperid snake venom in vitro and in vivo.  PLoS ONE.  9. 2014
• Venomous snakes of Costa Rica: Biological and medical implications of their venom proteomic profiles analyzed through the strategy of snake venomics.  Journal of Proteomics.  105:323-339. 2014
• Amino acid sequence and biological characterization of BlatPLA2, a non-toxic acidic phospholipase A2 from the venom of the arboreal snake Bothriechis lateralis from Costa Rica.  Toxicon.  73:71-80. 2013
• Muscle phospholipid hydrolysis by Bothrops asper Asp49 and Lys49 phospholipase A2 myotoxins - Distinct mechanisms of action.  FEBS Journal.  280:3878-3886. 2013
• Why myotoxin-containing snake venoms possess powerful nucleotidases?.  Biochemical and Biophysical Research Communications.  430:1289-1293. 2013
• 210. Understanding the Preclinical Efficacy Profile of Antivenoms: From the Lethality Potency Assay to Antivenomics.  Toxicon.  60:203. 2012
• A Lys49-PLA2 myotoxin of Bothrops asper triggers a rapid death of macrophages that involves autocrine purinergic receptor signaling.  Cell Death and Disease.  3. 2012
• Comparative proteomic analysis of the venom of the taipan snake, Oxyuranus scutellatus, from Papua New Guinea and Australia: Role of neurotoxic and procoagulant effects in venom toxicity.  Journal of Proteomics.  75:2128-2140. 2012
• Envenomations by bothrops and crotalus snakes induce the release of mitochondrial alarmins.  PLoS Neglected Tropical Diseases.  6. 2012
• Venomic and antivenomic analyses of the Central American coral snake, Micrurus nigrocinctus (Elapidae).  Journal of Proteome Research.  10:1816-1827. 2011
• Antivenomics of Atropoides mexicanus and Atropoides picadoi snake venoms: Relationship to the neutralization of toxic and enzymatic activities.  Investigación y desarrollo en ciencias exactas y naturales.  1:8-17. 2010
• Isolation of an acidic phospholipase A2 from the venom of the snake Bothrops asper of Costa Rica: Biochemical and toxicological characterization.  Biochimie.  92:273-283. 2010
• Snake venomics of bothriechis nigroviridis reveals extreme variability among palm pitviper venoms: Different evolutionary solutions for the same trophic purpose.  Journal of Proteome Research.  9:4234-4241. 2010
• Molecular configuration transitions of a nematic liquid crystal encapsulated in organically modified silicas.  Physical Chemistry Chemical Physics.  11:6234-6241. 2009