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Mapa de la ciencia

Herrera Arias, Cristina

Doctorado

posiciones

Investigación y desarrollo en ciencias exactas y naturales, Instituto Clodomiro Picado Twight (ICP) , Universidad de Costa Rica (UCR)
Investigación y desarrollo en ciencias de la salud, Escuela de Medicina, UCR , Universidad de Costa Rica (UCR) 2014 -

Investigadora en la Facultad de Farmacia, Universidad de Costa Rica.

Áreas de interés: Mecanismo de acción de metaloproteinasa hemorrágicas de venenos de serpientes. Evaluación de actividad farmacológica en modelos in vivo e in vitro: actividad hipoglicemiante, actividad antihipertensiva, actividad antioxidante, actividad antiinflamatoria y actividad contra mordedura de serpiente.

Áreas de investigación

Enfoque geográfico

Costa Rica Autogobierno

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publicaciones seleccionadas

artículo académico
- Analgesic effect of morphine and tramadol in standard toxicity assays in mice injected with venom of the snake Bothrops asper. Toxicon. 154:35-41. 2018
- Metalloproteinases in disease: identification of biomarkers of tissue damage through proteomics. Expert Review of Proteomics. 15:967-982. 2018
- Phosphorylation status of fetuin-A is critical for inhibition of insulin action and is correlated with obesity and insulin resistance. AJP Endocrinology and Metabolism. 317:E250-E260. 2018
- Unresolved issues in the understanding of the pathogenesis of local tissue damage induced by snake venoms. Toxicon. 148:123-131. 2018
- Effects of PI and PIII Snake Venom Haemorrhagic Metalloproteinases on the Microvasculature: A Confocal Microscopy Study on the Mouse Cremaster Muscle. PLoS ONE. 11. 2016
- A comprehensive view of the structural and functional alterations of extracellular matrix by snake venom metalloproteinases (SVMPs): Novel perspectives on the pathophysiology of envenoming. Toxins. 8. 2016
- Muscle Tissue Damage Induced by the Venom of Bothrops asper: Identification of Early and Late Pathological Events through Proteomic Analysis. PLoS Neglected Tropical Diseases. 10. 2016
- Viperid Envenomation Wound Exudate Contributes to Increased Vascular Permeability via a DAMPs/TLR-4 Mediated Pathway. Toxins. 8:349. 2016
- Tissue Localization and Extracellular Matrix Degradation by PI, PII and PIII Snake Venom Metalloproteinases: Clues on the Mechanisms of Venom-Induced Hemorrhage. PLoS Neglected Tropical Diseases. 9. 2015
- The analgesics morphine and tramadol do not alter the acute toxicity induced by Bothrops asper snake venom in mice. Toxicon. 81:54-57. 2014
- Systemic effects induced by the venom of the snake Bothrops caribbaeus in a murine model. Toxicon. 63:19-31. 2013