During the last decade and nowadays an enormous research effort has been deployed to the porous materials. Design, pores sizes, shapes, morphology and density are crucial features to increase the surface material, which helps to improve adsorption and absorption properties and helps the interaction of living cells with the porous material. To achieve this goal, the use of coatings with gold and silver nanoparticles or nanofilms can increase the level of biocompatibility or biotoxicity, especially due to their effect on cell adhesion and proliferation. The biocompatibility and other properties obtained for nanoparticles application coatings are related to the particle size. Gold and silver nanoparticles are size controlled when a colloid is form and later this particles are immobilized on a porous silicone matrix, the pH, temperature, concentration, and proportion or ratio between the metal compound and the stabilizer or reducing agent are factors to consider for a gold and silver particles control on the colloid formation, an lather on the immobilization of these particles over a porous silicone matrix to obtain hybrid nanostructures that combine the best properties from porous polymers and metal particles based on the application.
