Abstracto
- Licania platypus, locally known as " Traditionally, it has been used different anatomical parts in Central America for a variety of health problems, especially gastrointestinal problems. Aim: To investigate the possible gastric antiulcer act Methods: Gastric lesions were induced by ethanol and indomethacin models. Also the extract was evaluated in modified Shay rat model. Licania platypus were measured. Besides, other parameters were analyzed in pylorus Results: Oral administration of a unique dose of ethanol extract (500 mg/kg) significantly reduced the area of gastric lesions (p < 0.05) on ethanol and indomethacin significant increase of the gastric mucus secretion in modified Shay model (p < 0.05). Conclusion: Licania platypus ethanol extract exerted a gastroprotective induction models. This work provides the first evidence that species of activity and permits further studies to elucidate a specific mechanism.